Setback

Noun

 * 1) An obstacle, delay, or disadvantage.
 * After some initial setbacks, the expedition went safely on its way.
 * 1) The required distance between a structure and a road.


 * 1) (possibly archaic) A backset; a countercurrent; an eddy.
 * 2) A backset; a check; a repulse; a ; a relapse.

Thesaurus
arrest, arrestation, arrestment, atavism, backset, backsliding, backward deviation, backward motion, backward step, bafflement, balk, betrayed hope, blasted expectation, blighted hope, blockage, blocking, blow, buffet, check, checkmate, clogging, closing up, closure, comedown, confusion, constriction, cramp, cruel disappointment, dash, dashed hope, deceleration, defeat, delay, descent, detainment, detention, disappointment, discomfiture, disillusionment, dissatisfaction, down, drag, ease-off, ease-up, failure, fallen countenance, falling back, fiasco, fixation, fizzle, flagging, foil, foiling, foot-dragging, forlorn hope, frustration, hampering, hindering, hindrance, holdback, holdup, hope deferred, impediment, inhibition, interference, interruption, lag, lapse, let, letdown, letup, minus acceleration, mirage, negativism, nuisance value, obstacle, obstruction, obstructionism, occlusion, opposition, reaction, rebuff, recession, recidivation, recidivism, recrudescence, recurrence, reentry, refluence, reflux, regress, regression, relapse, renewal, repression, repulse, resistance, restraint, restriction, retardation, retardment, retroaction, retrocession, retroflexion, retrogradation, retrogression, retrusion, return, reversal, reverse, reverse of fortune, reversion, rollback, rout, severe check, slack-up, slackening, slowdown, slowing, slowing down, slowup, sore disappointment, squeeze, sternway, stranglehold, stricture, stumbling block, suppression, tantalization, tease, throwback

Etymology
From set + back

Translations

 * Scottish Gaelic:

Anagrams

 * backest