Careworn

Adjective

 * 1) Showing the signs of long-term stresses.

Adverbs for Careworn
sorely; sorrily; heartbreakingly; unbearably; piteously; bitterly; dismally; hopelessly; unutterably; tragically; extremely; incredibly; gravely; outrageously; indescribably; irritably; distressingly; intolerably; sadly; anxiously; uncomfortably; dejectedly; wretchedly; grievously; miserably; pitiably; horribly;

Thesaurus
exhausted, fagged, grief-stricken, griefful, grieved, grievous, heavy-laden, in grief, jaded, lamentable, lugubrious, mournful, pinched, plaintive, plangent, plunged in grief, rueful, sorrowed, sorrowful, sorrowing, tearful, troubled, tuckered, woeful, worn, aggrieved, anguished, distressed, doleful, dolorous, drawn, dumb with grief,

Etymology
care + worn